TacosNearYou

Guadalupe On Main

4.7(841)Hours not recordedA local favourite — 4.7★ from 841 reviews

Guadalupe On Main is a mexican restaurant in Mesa, AZ at 1526 E Main St, Mesa, AZ 85203. Hours not recorded. Rated 4.7 from 841 Google reviews. Call (480) 272-7220. Directions and full hours below.

Address
1526 E Main St, Mesa, AZ 85203, 85203
Phone
(480) 272-7220
Website
guadalupeonmain.com/
Type
Mexican restaurant · independent
DirectionsCallWebsite & menuMenu on Google

About Guadalupe On Main

Guadalupe On Main is a full Mexican restaurant, so tacos share the menu with combo plates, fajitas and sides. It sits in Mesa (85203), AZ, independently run.

Diners rate it 4.7 out of 5 across 841 reviews. That rating, weighted by how many people left it, is what places it where it is in our Mesa ranking.

Order tacos a la carte rather than in a combo if tacos are what you came for.

It is on E Main St in Mesa. Most sit-down spots this size have a lot or nearby street parking. Use the Directions button for turn-by-turn.

Call ahead or check the map listing before a special trip. Small mexican restaurants change hours often, and our data refreshes on a schedule, not live.

In our Mesa taco guide, Guadalupe On Main is ranked #23 of 95, by star rating weighted by review count. How we rank.

What to expect on the menu

We do not have Guadalupe On Main’s exact menu on file, so this is what a mexican restaurant of this kind typically serves, not a guarantee of today’s board:

For the real menu and prices, use the venue’s site or the Google listing.

Opening hours

We do not have Guadalupe On Main’s own hours on file. The quickest way to check is to call (480) 272-7220.

Menu

The current menu, prices and photos are on guadalupeonmain.com. You can also search Guadalupe On Main on Google or open its Google Maps listing for the menu, dish photos and recent reviews.

Closest taco spots to Guadalupe On Main

Straight-line distance from Guadalupe On Main, nearest first — useful if it is shut, the queue is long, or you want a second stop.

  1. La Casa del GuajoloteTaco shop · 1437 E Main St · 0.1 mi awayHours not recordedCallDirections
  2. Picante GrillMexican restaurant · 1127 E Main St, Mesa, AZ 85203 · 0.5 mi away4.9(701)Hours not recordedCallDirections
  3. Backyard TacoTaco shop · 1524 East University Drive · 0.5 mi away4.5(4,128)Hours not recordedCallDirections
  4. Blazing Desert DogsTaco shop · 1441 E Broadway Rd · 0.5 mi awayHours not recordedCallDirections
  5. Mr. Pancho Mexican FoodTaco shop · 1040 E Main St · 0.6 mi awayHours not recordedCallDirections
  6. La Carreta de Juquila OaxTaco shop · 1320 E Broadway Rd · 0.6 mi awayHours not recordedCallDirections

Get directionsSee all 95 taco spots in Mesa →

Guadalupe On Main: common questions

Is Guadalupe On Main open right now?

We do not have opening hours on record for Guadalupe On Main, so check its Google listing or call (480) 272-7220 before you go.

Where is Guadalupe On Main?

Guadalupe On Main is a mexican restaurant at 1526 E Main St, Mesa, AZ 85203, 85203 in Mesa, AZ. Use the Directions button for turn-by-turn from where you are.

How much do tacos cost at Guadalupe On Main?

We do not have prices on file for Guadalupe On Main. As a rule, a mexican restaurant in Mesa runs a few dollars a taco. Check its menu link for current pricing.

Does Guadalupe On Main do takeout or delivery?

Not on record. Most mexican restaurants do takeout at the counter; for delivery, check DoorDash or Uber Eats for your address.

Is Guadalupe On Main a chain?

No, Guadalupe On Main is independently run, not part of a chain.

How is Guadalupe On Main ranked?

Guadalupe On Main is #23 of 95 taco spots we track in Mesa, ordered by star rating weighted by review count. Nobody pays for placement. Full method on our How We Rank page.

Is this your restaurant, or spotted something wrong? The fastest fix is the public map record, or send us the correction. No charge to claim or update a listing.

Last updated September 29, 2026. Venue details refresh with each data import.